Laboratoř proteomiky kmenových buněk

Nemes D, Myšáková M, Minařík L, Jonášová A, Stopka T, Pimková KG. Redox-dependent protein S-glutathionylation governs azacitidine sensitivity and resistance in AML. Redox Biol. 2025 Dec 4;89:103958. doi: 10.1016/j.redox.2025.103958. (IF 11.9)

Bašová P, Minařík L, Magalhaes-Novais SC, Balounová J, Zemanová Z, Aghová T, Špaček M, Jonášová A, Pimková KG, Procházka J, Sedláček R, Stopka T. Investigating resistance to 5-Azacytidine and Venetoclax in PDX models of MDS/AML. Front Oncol. 2025 Jan 7;14:1414950. doi: 10.3389/fonc.2024.1414950. (IF 3.2)

Astapenko D, Vajrychova M, Fabrik I, Kupcik R, Pimkova K, Tambor V, Radochova V, Cerny V. Impact of anesthetics on rat hippocampus and neocortex: A comprehensive proteomic study based on label-free mass spectrometry. Heliyon. 2024 Mar 5;10(6):e27638. doi: 10.1016/j.heliyon.2024.e27638. (IF 4.0)

Turkova T, Kokavec J, Zikmund T, Dibus N, Pimkova K, Nemec D, Holeckova M, Ruskova L, Sedlacek R, Cermak L, Stopka T. Differential requirements for Smarca5 expression during hematopoietic stem cell commitment. Commun Biol. 2024 Feb 29;7(1):244. doi: 10.1038/s42003-024-05917-z. (IF 5.9)

Petra Bašová and Lubomír Minařík, Silvia Carina Magalhaes-Novais, Jana Balounová, Zuzana Zemanová, Tatiana Aghová, Martin Špaček, Anna Jonášová, Kristýna Gloc Pimková, Jan Procházka, Radislav Sedláček, Tomáš Stopka.Investigating Resistance to 5-Azacytidine and Venetoclax in PDX Models of MDS/AML. Front. Oncol. Sec. Hematologic Malignancies Volume 14 – 2024. doi:10.3389/fonc.2024.1414950 (IF 3.5)

Vajrychova M, Salovska B, Pimkova K, Fabrik I, Hodny Z. SILAC-IodoTMT for Assessment of the Cellular Proteome and Its Redox Status. Methods Mol Biol. 2023;2603:259-268. doi: 10.1007/978-1-0716-2863-8_21.

Pimkova K, Jassinskaja M, Munita R, Ciesla M, Guzzi N, Cao Thi Ngoc P, Vajrychova M, Johansson E, Bellodi C, Hansson J. Quantitative analysis of redox proteome reveals oxidation-sensitive protein thiols acting in fundamental processes of developmental hematopoiesis. Redox Biology. Volume 53, July 2022, 102343. ISSN 2213-2317. https://doi.org/10.1016/j.redox.2022.102343. (IF 11.79)

Salovska B, Kondelova A, Pimkova K, Liblova Z, Pribyl M, Fabrik I, Bartek J, Vajrychova M, Hodny Z. Peroxiredoxin 6 protects irradiated cells from oxidative stress and shapes their senescence-associated cytokine landscape. Redox Biol. 2022 Feb;49:102212. doi: 10.1016/j.redox.2021.102212. (IF 11.79)